Pyrazinamide may possess cardioprotective properties

Pyrazinamide may improve fluoroquinolone-based treatment of multidrug-resistant tuberculosis.

The role of pyrazinamide in the current treatment of multidrug-resistant (MDR) tuberculosis (TB) is uncertain. From a territory-wide registry of MDR-TB cases diagnosed between 1995 and 2009, we assembled a cohort of 194 patients with MDR pulmonary TB given fluoroquinolone-containing regimens. Stratified by pyrazinamide use and susceptibility, there were 83 users with pyrazinamide-susceptible MD...

Does Rhodiola rosea possess ergogenic properties?

Rhodiola rosea is an herb purported to possess adaptogenic and ergogenic properties and has recently been the subject of increased interest The purpose of this article was to review and summarize recent investigations of the potential performance-enhancing properties of Rhodiola rosea. Such studies have generated equivocal results. Several investigations conducted in Eastern Europe have indicat...

Cardioprotective effect of red wine may be mediated by urate.

Does zinc possess renoprotective properties in patients under cardiac surgery?

1. Ortega‐Loubon C, Fernández‐Molina M, Carrascal‐Hinojal Y, Fulquet‐Carreras E. Cardiac surgery‐associated acute kidney injury. Ann Card Anaesth 2016;19:687‐98. 2. Gaffney AM, Sladen RN. Acute kidney injury in cardiac surgery. Curr Opin Anaesthesiol 2015;28:50‐9. 3. Berger MM, Soguel L, Shenkin A, Revelly JP, Pinget C, Baines M, et al. Influence of early antioxidant supplements on clinical evo...

What properties should an overall measure of test performance possess?

To the Editor: Obuchowski et al. (1 ) recently reviewed the uses and misuses of ROC curves and explained, in simple terms, some sophisticated solutions to frequent problems, thereby popularizing tools described elsewhere, notably in the book coauthored by Nancy Obuchowski (2 ). What prompts me to comment on this careful and timely review are two fundamental questions: What properties should an ...